Gabriel Chan

Gabriel Chan

Machine Learning & Biomedical AI

Open to work: machine learning and medtech roles

Bridging clinical physiology and computer science. Building end-to-end diagnostic pipelines and custom AI architectures for healthcare data.

About Me

I build machine learning for healthcare data, with a background that spans the lab bench, medical device design and computer science. I care most about whether a model holds up on real clinical data, not just on a benchmark.

Data from the source

Before I modeled data, I generated it — crypt isolation, 3D organoid culture, microscopy-based quantification, in the Asfaha Lab at Western.

Models from first principles

I implemented LoRA from scratch and traced a rank-16 training collapse to its cause, and ran a controlled 8-model CNN ablation to isolate why batch norm and residual connections underperformed at this data scale.

Biomedical Device Development

On a Class III device project, I helped trace 240+ design inputs to tests and assess 60+ hazards.

Clear communication

I write to make dense material usable — from project documentation to a children's anatomy book translating physiology for readers aged 6–10.

Experience & Research

Apr 2025 — Aug 2025

Machine Learning Research Assistant · Krembil Brain Institute

Built an end-to-end Python pipeline to analyze brain MRI data for Parkinson's disease diagnosis, automating preprocessing, segmentation and radiomics feature extraction.

~55% → 85% Accuracy increase
L1 Feature selection
Python PyRadiomics Random Forest XGBoost
Jan 2025 — Apr 2025

Biomedical Device Development Project · University of Toronto (MEng)

In a team of 6, developed a Class III, MRI-guided brain tumour ablation device concept under ISO 13485. Contributed to design inputs, verification testing, and risk and hazard analysis, tracing market requirements to testing.

240+ Design inputs
200+ Planned V&V tests
ISO 13485 ISO 14971 Risk Analysis
Sep 2023 — Apr 2024

Honours Thesis · Western University (Asfaha Lab)

Compared R-spondin 1 and 3 effects on colonic organoid regeneration using organoids from colitis-model and control mice, quantifying organoid number, budding and size from serial microscopy images. Found significantly fewer organoids in R-spondin 3 cultures from colitis mice, contradicting prior in-vivo findings.

n=4 Per group
p < 0.05 Rspo3 vs. Rspo1, colitis
3D Organoid Culture Crypt Isolation Microscopy t-tests / ANOVA

Featured Projects

Skills Matrix

Programming & Languages

Python Java R Git/GitHub

Machine Learning & AI

PyTorch TensorFlow/Keras Hugging Face scikit-learn PEFT/LoRA CNNs

Clinical & Biomedical

PyRadiomics MRI Analysis Literature Review Biomedical Literature Analysis 3D Organoids Light Microscopy Animal Models Cell Culture

Regulated Environments

ISO 13485 ISO 14971 IEC 62304 Design Controls Verification and Validation

Education

Sep 2025 — Present

University of Pennsylvania

Master of Computer and Information Technology (Computer Science)

Sep 2024 — Aug 2025

University of Toronto

Master of Engineering, Biomedical Engineering

Sep 2020 — Jun 2024

Western University

Bachelor of Medical Sciences, Honours Specialization in Physiology and Pharmacology

Get in Touch

Open to Work

I'm actively looking for machine learning and medtech roles where I can combine clinical physiology, biomedical data pipelines and custom AI architecture. I'm especially interested in:

  • ML engineer or data scientist roles in health and biomedical settings, such as clinical imaging or biomedical text
  • Medical device and digital health teams that build regulated software or AI-enabled devices
  • Clinical and biomedical data analyst roles, working with research and clinical datasets

The best way to reach me is by email.

Say Hello / Email Me